thats not gonna do much of anything. there's only a slight chance something could've happened to all the files, in the scenario, I'm assuming, that you don't go mess around and accidentally delete stuff from the directory you installed it in.
anyway, odds are that its somethin to do with your computer itself. you might be low on resources, you might have one too many applications running while you're trying to load a game, which, now a days, a game eats the s*** outta your memory.
I can't really help you any further unless you give me your specs.