You are possibly not actually *setting* the value. In the new power tweaker, when you enter a new value you must press ENTER for it to "set".
For example, to change the transport wheel speed of a station I would select the station. Change the transport wheel speed from 10 to -1 and press ENTER while the cursor is still in that edit box. Then I would move on to another setting or segment. If you do not press ENTER after each value changed, it will not be "set".
Hope that helps
- Tia